Molecular weight (DA)
89kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ZNF148. AA range:61-110
Specificity
ZBP-89 Polyclonal Antibody detects endogenous levels of ZBP-89 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with HNRPDL.,
Function
function:Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with HNRPDL.,
Protein name
Zinc finger protein 148
Other name
ZNF148; ZBP89; Zinc finger protein 148; Transcription factor ZBP-89; Zinc finger DNA-binding protein 89
Human protein sequence Database
Q9UQR1
Mouse protein sequence database
Q61624
Rat protein sequence database
Q62806
Cellular localization
Nucleus.
Tissue expression
Epithelium,Insulinoma,Kidney,Peripheral blood,Primary B-Cells,Testis,
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