Molecular weight (DA)
38kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RPC4. AA range:281-330
Specificity
POLR3D Polyclonal Antibody detects endogenous levels of POLR3D protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line. It leads to a block in progression through the G1 phase of the cell cycle at nonpermissive temperatures. [provided by RefSeq, Jul 2008],
Function
function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.,similarity:Belongs to the eukaryotic RPC4/POLR3D RNA polymerase subunit family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). Interacts with POLR3E/RPC5.,
Protein name
DNA-directed RNA polymerase III subunit RPC4
Other name
POLR3D; BN51; BN51T; DNA-directed RNA polymerase III subunit RPC4; RNA polymerase III subunit C4; DNA-directed RNA polymerase III subunit D; Protein BN51; RNA polymerase III 47 kDa subunit; RPC53 homolog
Fields
>>RNA polymerase;>>Cytosolic DNA-sensing pathway
Human protein sequence Database
P05423
Mouse protein sequence database
Q91WD1
Rat protein sequence database
Cellular localization
Nucleus.
Tissue expression
Epithelium,Lung,Lymph,
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