Molecular weight (DA)
41kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TTC19 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein with a tetratricopeptide repeat (TPR) domain containing several TPRs of about 34 aa each. These repeats are found in a variety of organisms including bacteria, fungi and plants, and are involved in a variety of functions including protein-protein interactions. This protein is embedded in the inner mitochondrial membrane and is involved in the formation of the mitochondrial respiratory chain III. It has also been suggested that this protein plays a role in cytokinesis. Mutations in this gene cause mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2012],
Function
caution:It is uncertain whether Met-1 or Met-122 is the initiator.,similarity:Contains 5 TPR repeats.,
Protein name
Tetratricopeptide repeat protein 19, mitochondrial (TPR repeat protein 19)
Human protein sequence Database
Q6DKK2
Mouse protein sequence database
Q8CC21
Rat protein sequence database
D4A6D7
Cellular localization
Mitochondrion inner membrane .
Tissue expression
Brain,Muscle,