Molecular weight (DA)
32kD
Immunogen
Synthesized peptide derived from TWIK-3 . at AA range: 170-250
Specificity
TWIK-3 Polyclonal Antibody detects endogenous levels of TWIK-3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function
function:Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,
Protein name
Potassium channel subfamily K member 7
Other name
KCNK7; Potassium channel subfamily K member 7
Human protein sequence Database
Q9Y2U2
Mouse protein sequence database
Q9Z2T1
Rat protein sequence database
Cellular localization
Membrane ; Multi-pass membrane protein .
Tissue expression
Brain,PCR rescued clones,
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