Molecular weight (DA)
41kD
Immunogen
The antiserum was produced against synthesized peptide derived from human P2RY8. AA range:192-241
Specificity
P2RY8 Polyclonal Antibody detects endogenous levels of P2RY8 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
purinergic receptor P2Y8(P2RY8) Homo sapiens The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008],
Function
function:Probable receptor for purines coupled to G-proteins.,induction:Down-regulated during granulocytic regulation.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.,
Protein name
P2Y purinoceptor 8
Other name
P2RY8; P2Y purinoceptor 8; P2Y8
Fields
>>Neuroactive ligand-receptor interaction
Human protein sequence Database
Q86VZ1
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.
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