Immunogen
The antiserum was produced against synthesized peptide derived from human EPHA6. AA range:891-940
Specificity
EphA6 Polyclonal Antibody detects endogenous levels of EphA6 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-A family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Expressed in brain and testis.,
Function
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-A family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Expressed in brain and testis.,
Protein name
Ephrin type-A receptor 6
Other name
EPHA6; EHK2; HEK12; Ephrin type-A receptor 6; EPH homology kinase 2; EHK-2; EPH-like kinase 12; EK12
Human protein sequence Database
Q9UF33
Mouse protein sequence database
Q62413
Rat protein sequence database
P54758
Cellular localization
Membrane ; Single-pass type I membrane protein .
Tissue expression
Expressed in brain and testis.
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