Immunogen
The antiserum was produced against synthesized peptide derived from human GPR22. AA range:271-320
Specificity
GPR22 Polyclonal Antibody detects endogenous levels of GPR22 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein. [provided by RefSeq, Jul 2008],
Function
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:In the brain regions frontal cortex, caudate, putamen and thalamus; not in pons, hypothalamus and hippocampus.,
Protein name
Probable G-protein coupled receptor 22
Other name
GPR22; Probable G-protein coupled receptor 22
Human protein sequence Database
Q99680
Mouse protein sequence database
Q8BZL4
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
High expression in adult and fetal heart tissue (PubMed:18539757). Expressed in the brain, with enrichment in the accumbens, amygdala, cerebellum, cortex, and hippocampus regions (PubMed:9073069, PubMed:18539757).