Molecular weight (DA)
45kD
Immunogen
The antiserum was produced against synthesized peptide derived from human STK17B. AA range:251-300
Specificity
DRAK2 Polyclonal Antibody detects endogenous levels of DRAK2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Acts as a positive regulator of apoptosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CHP causing CHP to translocate from the Golgi to the nucleus.,tissue specificity:Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.,
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Acts as a positive regulator of apoptosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CHP causing CHP to translocate from the Golgi to the nucleus.,tissue specificity:Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.,
Protein name
Serine/threonine-protein kinase 17B
Other name
STK17B; DRAK2; Serine/threonine-protein kinase 17B; DAP kinase-related apoptosis-inducing protein kinase 2
Human protein sequence Database
O94768
Mouse protein sequence database
Q8BG48
Rat protein sequence database
Q91XS8
Cellular localization
Nucleus . Cell membrane . Endoplasmic reticulum-Golgi intermediate compartment . Colocalizes with STK17B at the plasma membrane. .
Tissue expression
Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
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