Molecular weight (DA)
13kD
Immunogen
Synthesized peptide derived from human Secretin
Specificity
This antibody detects endogenous levels of human Secretin
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the duodenum. This hormone stimulates the secretion of bile and bicarbonate in the duodenum, pancreatic and biliary ducts. [provided by RefSeq, Feb 2016],
Function
function:Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach.,online information:Secretin entry,similarity:Belongs to the glucagon family.,
Fields
>>Neuroactive ligand-receptor interaction;>>Pancreatic secretion;>>Bile secretion
Human protein sequence Database
P09683
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted .