Molecular weight (DA)
133kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
FLIP1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A.,similarity:Belongs to the FILIP1 family.,subunit:Interacts with FLNA.,tissue specificity:Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus.,
Function
function:By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A.,similarity:Belongs to the FILIP1 family.,subunit:Interacts with FLNA.,tissue specificity:Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus.,
Gene Name
FILIP1 KIAA1275
Protein name
Filamin-A-interacting protein 1 (FILIP)
Human protein sequence Database
Q7Z7B0
Mouse protein sequence database
Q9CS72
Rat protein sequence database
Q8K4T4
Cellular localization
Cytoplasm, cytoskeleton .
Tissue expression
Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus.
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