Molecular weight (DA)
46kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TRI31 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that functions as an E3 ubiquitin-protein ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Function
similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 RING-type zinc finger.,
Gene Name
TRIM31 C6orf13 RNF
Protein name
E3 ubiquitin-protein ligase TRIM31 (EC 6.3.2.-) (Tripartite motif-containing protein 31)
Human protein sequence Database
Q9BZY9
Mouse protein sequence database
Q8R0K2
Rat protein sequence database
Cellular localization
Cytoplasm . Mitochondrion . Predominantly expressed in the cytoplasm but a fraction is associated with the mitochondria.
Tissue expression
Up-regulated in gastric adenocarcinomas.
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