Molecular weight (DA)
41kD
Immunogen
The antiserum was produced against synthesized peptide derived from human TBPL2. AA range:81-130
Specificity
TBPL2 Polyclonal Antibody detects endogenous levels of TBPL2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.,similarity:Belongs to the TBP family.,subcellular location:Present in the cytoplasm during cytokenesis.,subunit:Interacts with TAF3.,tissue specificity:Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes.,
Function
function:Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.,similarity:Belongs to the TBP family.,subcellular location:Present in the cytoplasm during cytokenesis.,subunit:Interacts with TAF3.,tissue specificity:Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes.,
Protein name
TATA box-binding protein-like protein 2
Other name
TBPL2; TBP2; TRF3; TATA box-binding protein-like protein 2; TBP-like protein 2; TATA box-binding protein-related factor 3; TBP-related factor 3
Fields
>>Basal transcription factors;>>Huntington disease;>>Spinocerebellar ataxia;>>Human papillomavirus infection;>>Human T-cell leukemia virus 1 infection;>>Viral carcinogenesis
Human protein sequence Database
Q6SJ96
Mouse protein sequence database
Q6SJ95
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus . Present in the cytoplasm during cytokinesis. .
Tissue expression
Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes.