Molecular weight (DA)
33kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 220-300
Specificity
CENPO Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
Function
function:Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.,subcellular location:Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.,subunit:Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU.,
Gene Name
CENPO ICEN36 MCM21R
Protein name
Centromere protein O (CENP-O) (Interphase centromere complex protein 36)
Human protein sequence Database
Q9BU64
Mouse protein sequence database
Q8K015
Rat protein sequence database
Cellular localization
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Tissue expression
Lung,Placenta,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车