Molecular weight (DA)
47kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CKI-gamma2. AA range:10-59
Specificity
Casein Kinase Iγ2 Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,tissue specificity:Testis.,
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,tissue specificity:Testis.,
Protein name
Casein kinase I isoform gamma-2
Abbreviation
Casein Kinase Iγ2
Other name
CSNK1G2; CK1G2; Casein kinase I isoform gamma-2; CKI-gamma 2
Fields
>>Hedgehog signaling pathway
Human protein sequence Database
P78368
Mouse protein sequence database
Q8BVP5
Rat protein sequence database
Q62762
Cellular localization
Cytoplasm, cell cortex . Cytoplasm .
Tissue expression
Testis.
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