Molecular weight (DA)
119kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 500-580
Specificity
MKL2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
domain:The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity.,function:Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.,PTM:O-glycosylated.,similarity:Contains 1 SAP domain.,similarity:Contains 3 RPEL repeats.,subunit:Interacts with MKL1 and SRF.,
Function
domain:The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity.,function:Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.,PTM:O-glycosylated.,similarity:Contains 1 SAP domain.,similarity:Contains 3 RPEL repeats.,subunit:Interacts with MKL1 and SRF.,
Gene Name
MKL2 KIAA1243 MRTFB
Protein name
MKL/myocardin-like protein 2 (Megakaryoblastic leukemia 2) (Myocardin-related transcription factor B) (MRTF-B)
Human protein sequence Database
Q9ULH7
Mouse protein sequence database
P59759
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Amygdala,Brain,Cervix carcinoma,Epithelium,Medulla oblongata,Normal pituitary,Pancr
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