Molecular weight (DA)
18kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 100-180
Specificity
HSPB7 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Belongs to the small heat shock protein (HSP20) family.,subunit:Interacts with C-terminal domain of actin-binding protein 280.,tissue specificity:Isoform 1 is highly expressed in adult and fetal heart, skeletal muscle, and at a much lower levels in adipose tissue and in aorta. Undetectable in other tissues. Isoform 2 and isoform 3 are poorly detected in heart.,
Function
similarity:Belongs to the small heat shock protein (HSP20) family.,subunit:Interacts with C-terminal domain of actin-binding protein 280.,tissue specificity:Isoform 1 is highly expressed in adult and fetal heart, skeletal muscle, and at a much lower levels in adipose tissue and in aorta. Undetectable in other tissues. Isoform 2 and isoform 3 are poorly detected in heart.,
Protein name
Heat shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp)
Human protein sequence Database
Q9UBY9
Mouse protein sequence database
P35385
Rat protein sequence database
Q9QUK5
Cellular localization
Cytoplasm . Nucleus . Nucleus, Cajal body . Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Tissue expression
Isoform 1 is highly expressed in adult and fetal heart, skeletal muscle, and at a much lower levels in adipose tissue and in aorta. Undetectable in other tissues. Isoform 2 and isoform 3 are poorly detected in heart.
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