Molecular weight (DA)
22kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Specificity
TPD53 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2016],
Function
similarity:Belongs to the TPD52 family.,subunit:Forms homodimer or heterodimer with other members of the family.,
Protein name
Tumor protein D53 (hD53) (Tumor protein D52-like 1)
Human protein sequence Database
Q16890
Mouse protein sequence database
O54818
Rat protein sequence database
Cellular localization
cytoplasm,perinuclear region of cytoplasm,
Tissue expression
Liver,Lung,Mammary carcinoma,Skeletal muscle,
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