Molecular weight (DA)
36kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RSU1. AA range:187-236
Specificity
Rsu-1 Polyclonal Antibody detects endogenous levels of Rsu-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008],
Function
function:Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro.,similarity:Contains 7 LRR (leucine-rich) repeats.,
Protein name
Ras suppressor protein 1
Other name
RSU1; RSP1; Ras suppressor protein 1; RSP-1; Rsu-1
Human protein sequence Database
Q15404
Mouse protein sequence database
Q01730
Rat protein sequence database
Cellular localization
cytosol,focal adhesion,extracellular exosome,
Tissue expression
Adipocyte,Blood vessels- blood vessel,Brain,Eye,Platelet,Skin,Thalamus,Trachea,
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