Molecular weight (DA)
88kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CPT1B. AA range:401-450
Specificity
CPTI-M Polyclonal Antibody detects endogenous levels of CPTI-M protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009],
Function
catalytic activity:ATP + choline = ADP + O-phosphocholine.,catalytic activity:ATP + ethanolamine = ADP + O-phosphoethanolamine.,catalytic activity:Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.,miscellaneous:This protein is produced by a bicistronic gene which also produces the CHKB protein from a non-overlapping reading frame.,miscellaneous:This protein is produced by a bicistronic gene which also produces the CPT1B protein from a non-overlapping reading frame.,pathway:Lipid metabolism; fatty acid beta-oxidation.,similarity:Belongs to the carnitine/choline acetyltransferase family.,similarity:Belongs to the choline/ethanolamine kinase family.,tissue specificity:Strong expression in heart and skeletal muscle. No expression in liver and kidney.,
Protein name
Carnitine O-palmitoyltransferase 1 muscle isoform
Other name
CPT1B; KIAA1670; Carnitine O-palmitoyltransferase 1; muscle isoform; CPT1-M; Carnitine O-palmitoyltransferase I, muscle isoform; CPT I; CPTI-M; Carnitine palmitoyltransferase 1B; Carnitine palmitoyltransferase I-like protein
Fields
>>Fatty acid degradation;>>Fatty acid metabolism;>>PPAR signaling pathway;>>AMPK signaling pathway;>>Thermogenesis;>>Adipocytokine signaling pathway;>>Glucagon signaling pathway;>>Insulin resistance;>>Alcoholic liver disease;>>Diabetic cardiomyopathy
Human protein sequence Database
Q92523
Mouse protein sequence database
Q924X2
Rat protein sequence database
Cellular localization
Mitochondrion outer membrane ; Multi-pass membrane protein .
Tissue expression
Strong expression in heart and skeletal muscle. No expression in liver and kidney.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车