Immunogen
The antiserum was produced against synthesized peptide derived from human NCAPG2. AA range:561-610
Specificity
hCAP-G2 Polyclonal Antibody detects endogenous levels of hCAP-G2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
non-SMC condensin II complex subunit G2(NCAPG2) Homo sapiens This gene encodes a protein that belongs to the Condensin2nSMC family of proteins. The encoded protein is a regulatory subunit of the condensin II complex which, along with the condensin I complex, plays a role in chromosome assembly and segregation during mitosis. A similar protein in mouse is required for early development of the embryo. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
Function
function:Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.,similarity:Contains 1 HEAT repeat.,subunit:Component of the condensin-2 complex, which contains the SMC2 and SMC4 heterodimer, and 3 non SMC subunits that probably regulate the complex: NCAPH2, NCAPD3 and NCAPG2.,
Protein name
Condensin-2 complex subunit G2
Other name
NCAPG2; LUZP5; Condensin-2 complex subunit G2; Chromosome-associated protein G2; CAP-G2; hCAP-G2; Leucine zipper protein 5; Non-SMC condensin II complex subunit G2
Human protein sequence Database
Q86XI2
Mouse protein sequence database
Q6DFV1
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Endometrium,Epithelium,Ovary,Testis,
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