Molecular weight (DA)
131kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 320-400
Specificity
IGSF3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is an immunoglobulin-like membrane protein containing several V-type Ig-like domains. A mutation in this gene has been associated with bilateral nasolacrimal duct obstruction (LCDD). [provided by RefSeq, Jun 2016],
Function
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,miscellaneous:Likely interchromosomal Alu-mediated fusion between IGSF3 on 1p13.1 and GGT on 22q11.2. Breakpoints occurred inside Alu elements as well as in the 5' or 3' ends of them.,similarity:Contains 8 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in a wide range of tissues with High expression in Placenta, kidney and lung.,
Gene Name
IGSF3 EWI3 KIAA0466
Protein name
Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3)
Human protein sequence Database
O75054
Mouse protein sequence database
Q6ZQA6
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein .
Tissue expression
Expressed in a wide range of tissues with High expression in Placenta, kidney and lung.
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