Molecular weight (DA)
12kD
Immunogen
The antiserum was produced against synthesized peptide derived from human BRP44L. AA range:11-60
Specificity
Brp44L Polyclonal Antibody detects endogenous levels of Brp44L protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012],
Function
similarity:Belongs to the UPF0041 (0-44) family.,
Protein name
Mitochondrial pyruvate carrier 1
Other name
MPC1; BRP44L; CGI-129; HSPC040; PNAS-115; Mitochondrial pyruvate carrier 1; Brain protein 44-like protein
Fields
>>Diabetic cardiomyopathy
Human protein sequence Database
Q9Y5U8
Mouse protein sequence database
P63030
Rat protein sequence database
P63031
Cellular localization
Mitochondrion inner membrane ; Multi-pass membrane protein .
Tissue expression
Placenta,Promyelocytic leukemia,Skeletal muscle,Umbilical cord blood,
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