Molecular weight (DA)
123kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SDCG1. AA range:881-930
Specificity
NY-CO-1 Polyclonal Antibody detects endogenous levels of NY-CO-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a component of the ribosome quality control complex. The encoded protein facilitates the recognition and ubiquitination of stalled 60S subunits by the ubiquitin ligase listerin. A similar protein in fly functions as a tumor suppressor. [provided by RefSeq, Jul 2016],
Protein name
Nuclear export mediator factor NEMF
Other name
NEMF; SDCCAG1; Nuclear export mediator factor NEMF; Antigen NY-CO-1; Serologically defined colon cancer antigen 1
Human protein sequence Database
O60524
Mouse protein sequence database
Q8CCP0
Rat protein sequence database
Cellular localization
Cytoplasm, cytosol . Nucleus .
Tissue expression
Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.
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