Molecular weight (DA)
23kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CD83. AA range:101-150
Specificity
CD83 Polyclonal Antibody detects endogenous levels of CD83 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Function
function:May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.,online information:CD83 antigen,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Monomer.,tissue specificity:Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.,
Protein name
CD83 antigen
Other name
CD83; CD83 antigen; hCD83; B-cell activation protein; Cell surface protein HB15; CD antigen CD83
Human protein sequence Database
Q01151
Mouse protein sequence database
O88324
Rat protein sequence database
Cellular localization
Membrane; Single-pass type I membrane protein.
Tissue expression
Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.
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