Molecular weight (DA)
30kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RAB5C. AA range:122-171
Specificity
Rab 5C Polyclonal Antibody detects endogenous levels of Rab 5C protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010],
Function
function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Binds EEA1.,
Protein name
Ras-related protein Rab-5C
Other name
RAB5C; RABL; Ras-related protein Rab-5C; L1880; RAB5L
Fields
>>Ras signaling pathway;>>Endocytosis;>>Phagosome;>>Vasopressin-regulated water reabsorption;>>Salmonella infection;>>Amoebiasis;>>Tuberculosis
Human protein sequence Database
P51148
Mouse protein sequence database
P35278
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
Tissue expression
Brain,Lung,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车