Molecular weight (DA)
55kD
Immunogen
The antiserum was produced against synthesized peptide derived from human G3BP2. AA range:433-482
Specificity
G3BP2 Polyclonal Antibody detects endogenous levels of G3BP2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Probable scaffold protein that may be involved in mRNA transport .,PTM:Arg-457 and Arg-468 are dimethylated, probably to asymmetric dimethylarginine.,similarity:Contains 1 NTF2 domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Binds to the N-terminal domain of I-kappa-B-alpha.,
Function
function:Probable scaffold protein that may be involved in mRNA transport .,PTM:Arg-457 and Arg-468 are dimethylated, probably to asymmetric dimethylarginine.,similarity:Contains 1 NTF2 domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Binds to the N-terminal domain of I-kappa-B-alpha.,
Protein name
Ras GTPase-activating protein-binding protein 2
Other name
G3BP2; KIAA0660; Ras GTPase-activating protein-binding protein 2; G3BP-2; GAP SH3 domain-binding protein 2
Human protein sequence Database
Q9UN86
Mouse protein sequence database
P97379
Rat protein sequence database
Cellular localization
Cytoplasm . Cytoplasm, Stress granule .
Tissue expression
B-cell,Brain,Colon carcinoma,Epithelium,Lung carcinoma,Ovarian carc