Molecular weight (DA)
75kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RHG18. AA range:517-566
Specificity
ARHGAP18 Polyclonal Antibody detects endogenous levels of ARHGAP18 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).[supplied by OMIM, Apr 2010],
Function
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 Rho-GAP domain.,subunit:Interacts with MPHOSPH6.,
Protein name
Rho GTPase-activating protein 18
Other name
ARHGAP18; Rho GTPase-activating protein 18; MacGAP; Rho-type GTPase-activating protein 18
Human protein sequence Database
Q8N392
Mouse protein sequence database
Q8K0Q5
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Brain,Mast cell,Melanoma,Uterus,
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