Molecular weight (DA)
25kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human XCL1/XCL2. AA range:51-100
Specificity
Lymphotactin Polyclonal Antibody detects endogenous levels of Lymphotactin protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014],
Function
function:Chemotactic activity for lymphocytes but not for monocytes or neutrophils.,online information:XCL1 entry,similarity:Belongs to the intercrine gamma family.,tissue specificity:Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.,
Protein name
Lymphotactin/Cytokine SCM-1 beta
Abbreviation
Lymphotactin
Other name
XCL1; LTN; SCYC1; Lymphotactin; ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1; XCL2; SCYC2; Cytokine SCM-1 beta; C motif chemokine 2; XC chemokine ligand 2
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway
Human protein sequence Database
P47992
Mouse protein sequence database
P47993
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.
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