Immunogen
Synthesized peptide derived from the Internal region of human Relaxin 3.
Specificity
Relaxin 3 Polyclonal Antibody detects endogenous levels of Relaxin 3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
relaxin 3(RLN3) Homo sapiens This gene encodes a member of the relaxin family of insulin-like hormones that is expressed predominantly in the brain and plays a role in physiological processes such as stress, memory and appetite regulation. The encoded protein is a precursor that is proteolytically processed to generate a heterodimeric mature form consisting A and B chains interlinked by disulfide bonds. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015],
Function
function:May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142).,similarity:Belongs to the insulin family.,subunit:Heterodimer of a B chain and an A chain linked by two disulfide bonds.,
Other name
RLN3; INSL7; RXN3; ZINS4; Relaxin-3; Insulin-like peptide INSL7; Insulin-like peptide 7; Prorelaxin H3
Fields
>>Neuroactive ligand-receptor interaction;>>Relaxin signaling pathway
Human protein sequence Database
Q8WXF3
Mouse protein sequence database
Q8CHK2
Rat protein sequence database
Cellular localization
Secreted.
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