Molecular weight (DA)
80kD
Immunogen
Synthesized peptide derived from PREP . at AA range: 10-90
Specificity
PREP Polyclonal Antibody detects endogenous levels of PREP protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides. [provided by RefSeq, Jul 2008],
Function
catalytic activity:Hydrolysis of Pro-|-Xaa >> Ala-|-Xaa in oligopeptides.,function:Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.,PTM:The N-terminus is blocked.,similarity:Belongs to the peptidase S9A family.,subunit:Monomer.,
Protein name
Prolyl endopeptidase
Other name
PREP; PEP; Prolyl endopeptidase; PE; Post-proline cleaving enzyme
Human protein sequence Database
Q8N6D4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
nucleus,cytoplasm,membrane,
Tissue expression
Blood,Brain,Lymphocyte,Skin,
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