Molecular weight (DA)
34kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NKX6.3. AA range:161-210
Specificity
Nkx-6.3 Polyclonal Antibody detects endogenous levels of Nkx-6.3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The NKX family of homeodomain proteins controls numerous developmental processes. Members of the NKX6 subfamily, including NKX6-3, are involved in development of the central nervous system (CNS), gastrointestinal tract, and pancreas (Alanentalo et al., 2006 [PubMed 16326147]).[supplied by OMIM, Mar 2008],
Function
function:Putative transcription factor, which may be involved in patterning of central nervous system and pancreas.,similarity:Contains 1 homeobox DNA-binding domain.,
Protein name
Homeobox protein Nkx-6.3
Other name
NKX6-3; Homeobox protein Nkx-6.3
Human protein sequence Database
A6NJ46
Mouse protein sequence database
Q3UHX8
Rat protein sequence database
Cellular localization
Nucleus .