Molecular weight (DA)
17kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TPC6B Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
TRAPPC6B is a component of TRAPP complexes, which are tethering complexes involved in vesicle transport (Kummel et al., 2005 [PubMed 16025134]).[supplied by OMIM, Mar 2008],
Function
function:May play a role in vesicular transport from endoplasmic reticulum to Golgi.,similarity:Belongs to the TRAPP small subunits family. BET3 subfamily.,subunit:Part of the multisubunit TRAPP (transport protein particle) complex. Homodimer. Heterodimer with TRAPPC3.,
Protein name
Trafficking protein particle complex subunit 6B
Human protein sequence Database
Q86SZ2
Mouse protein sequence database
Q9D289
Rat protein sequence database
Cellular localization
Golgi apparatus, cis-Golgi network . Endoplasmic reticulum .
Tissue expression
Both isoforms are expressed ubiquitously (at transcript level), isoform 1 being the most predominant (PubMed:28626029). Expressed in the fetal brain and different regions of the adult brain and spinal cord (PubMed:28626029).
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