Molecular weight (DA)
28kD
Immunogen
The antiserum was produced against synthesized peptide derived from human HOXD12. AA range:191-240
Specificity
HoxD12 Polyclonal Antibody detects endogenous levels of HoxD12 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008],
Function
function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Abd-B homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
Protein name
Homeobox protein Hox-D12
Other name
HOXD12; HOX4H; Homeobox protein Hox-D12; Homeobox protein Hox-4H
Human protein sequence Database
P35452
Mouse protein sequence database
P23812
Rat protein sequence database
Cellular localization
Nucleus.
Tissue expression
PCR rescued clones,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车