Molecular weight (DA)
60kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SRPK3. AA range:261-310
Specificity
SRPK3 Polyclonal Antibody detects endogenous levels of SRPK3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Required for normal muscle development.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,tissue specificity:Exclusively expressed in skeletal and heart muscle.,
Protein name
SRSF protein kinase 3
Other name
SRPK3; MSSK1; STK23; SRSF protein kinase 3; Muscle-specific serine kinase 1; MSSK-1; Serine/arginine-rich protein-specific kinase 3; SR-protein-specific kinase 3; Serine/threonine-protein kinase 23
Human protein sequence Database
Q9UPE1
Mouse protein sequence database
Q9Z0G2
Rat protein sequence database
Tissue expression
Exclusively expressed in skeletal and heart muscle.
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