Molecular weight (DA)
105kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 620-700
Specificity
RAIN Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation.,similarity:Contains 1 dilute domain.,similarity:Contains 1 Ras-associating domain.,subcellular location:Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.,subunit:Interacts with Ras family members that have been activated by GTP binding. Interacts with HRAS, RAP1A, RAP2, RRAS, RAF1 and RRAS2.,tissue specificity:Highly expressed in heart. Detected at lower levels in placenta and pancreas.,
Function
function:May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation.,similarity:Contains 1 dilute domain.,similarity:Contains 1 Ras-associating domain.,subcellular location:Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.,subunit:Interacts with Ras family members that have been activated by GTP binding. Interacts with HRAS, RAP1A, RAP2, RRAS, RAF1 and RRAS2.,tissue specificity:Highly expressed in heart. Detected at lower levels in placenta and pancreas.,
Protein name
Ras-interacting protein 1 (Rain)
Human protein sequence Database
Q5U651
Mouse protein sequence database
Q3U0S6
Rat protein sequence database
Cellular localization
Cytoplasm, perinuclear region . Golgi apparatus, Golgi stack . Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.
Tissue expression
Highly expressed in heart. Detected at lower levels in placenta and pancreas.
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