Molecular weight (DA)
95kD
Immunogen
The antiserum was produced against synthesized peptide derived from human JAKMIP2. AA range:761-810
Specificity
Jamip2 Polyclonal Antibody detects endogenous levels of Jamip2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
Function
similarity:Belongs to the JAKMIP family.,tissue specificity:Highly expressed in brain, moderately expressed in thymus, spleen and lung, and weakly expressed in kidney, liver and peripheral blood lymphocytes. Aslo expressed in adrenal and pituitary glands, as well as testis.,
Protein name
Janus kinase and microtubule-interacting protein 2
Other name
JAKMIP2; JAMIP2; KIAA0555; NECC1; Janus kinase and microtubule-interacting protein 2; CTCL tumor antigen HD-CL-04; Neuroendocrine long coiled-coil protein 1
Human protein sequence Database
Q96AA8
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Golgi apparatus .
Tissue expression
Highly expressed in brain, moderately expressed in thymus, spleen and lung, and weakly expressed in kidney, liver and peripheral blood lymphocytes. Also expressed in adrenal and pituitary glands, as well as testis.