Molecular weight (DA)
18kD
Immunogen
Synthesized peptide derived from ACYP2 . at AA range: 40-120
Specificity
ACYP2 Polyclonal Antibody detects endogenous levels of ACYP2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016],
Function
catalytic activity:An acylphosphate + H(2)O = a carboxylate + phosphate.,function:Its physiological role is not yet clear.,similarity:Belongs to the acylphosphatase family.,similarity:Contains 1 acylphosphatase-like domain.,
Protein name
Acylphosphatase-2
Other name
ACYP2; ACYP; Acylphosphatase-2; Acylphosphatase; muscle type isozyme; Acylphosphate phosphohydrolase 2
Fields
>>Pyruvate metabolism;>>Metabolic pathways
Human protein sequence Database
P14621
Mouse protein sequence database
P56375
Rat protein sequence database
P35745
Cellular localization
mitochondrion,
Tissue expression
Heart,Muscle,Ovary,
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