Molecular weight (DA)
41kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 150-230
Specificity
SP6 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
SP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008],
Function
function:Promotes cell proliferation.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,tissue specificity:Ubiquitous.,
Protein name
Transcription factor Sp6 (Krueppel-like factor 14)
Human protein sequence Database
Q3SY56
Mouse protein sequence database
Q9ESX2
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Ubiquitous.
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