Molecular weight (DA)
83kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
IMMT Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed: 22114354, PubMed: 25781180).
Gene Name
IMMT HMP MINOS2 PIG4 PIG52
Protein name
Mitochondrial inner membrane protein (Cell proliferation-inducing gene 4/52 protein) (Mitofilin) (p87/89)
Human protein sequence Database
Q16891
Mouse protein sequence database
Q8CAQ8
Rat protein sequence database
Q3KR86
Cellular localization
Mitochondrion inner membrane ; Single-pass membrane protein . Mitochondrion .
Tissue expression
B-cell lymphoma,Bone marrow,Brain,Cajal-Retzius cell,Cervix,Colon e