Molecular weight (DA)
20kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human LAIR2. AA range:21-70
Specificity
CD306 Polyclonal Antibody detects endogenous levels of CD306 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013],
Function
alternative products:Named isoforms=2,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,
Protein name
Leukocyte-associated immunoglobulin-like receptor 2
Other name
LAIR2; CD306; Leukocyte-associated immunoglobulin-like receptor 2; LAIR-2; CD306
Human protein sequence Database
Q6ISS4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted.
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