Immunogen
The antiserum was produced against synthesized peptide derived from human LY6E. AA range:17-66
Specificity
TSA-1 Polyclonal Antibody detects endogenous levels of TSA-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
induction:By retinoic acid; in promyelocytic leukemia NB4 and in myeloblast HL-60 cell lines. Activated by IFN-alpha in monocytic cell line U-937 and in peripheral blood monocyte cells.,similarity:Contains 1 UPAR/Ly6 domain.,tissue specificity:Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes.,
Function
induction:By retinoic acid; in promyelocytic leukemia NB4 and in myeloblast HL-60 cell lines. Activated by IFN-alpha in monocytic cell line U-937 and in peripheral blood monocyte cells.,similarity:Contains 1 UPAR/Ly6 domain.,tissue specificity:Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes.,
Protein name
Lymphocyte antigen 6E
Other name
LY6E; 9804; RIGE; SCA2; TSA1; Lymphocyte antigen 6E; Ly-6E; Retinoic acid-induced gene E protein; RIG-E; Stem cell antigen 2; SCA-2; Thymic shared antigen 1; TSA-1
Human protein sequence Database
Q16553
Mouse protein sequence database
Q64253
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor, GPI-anchor .
Tissue expression
Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes.
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