Molecular weight (DA)
40kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 110-190
Specificity
GPR45 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system. [provided by RefSeq, Jul 2008],
Function
function:Orphan receptor. May play a role in brain function.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain; detected in the basal forebrain, frontal cortex, and caudate, but not in thalamus, hippocampus, or putamen.,
Protein name
Probable G-protein coupled receptor 45 (PSP24-1) (PSP24-alpha)
Human protein sequence Database
Q9Y5Y3
Mouse protein sequence database
Q9EQQ4
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Expressed in brain; detected in the basal forebrain, frontal cortex, and caudate, but not in thalamus, hippocampus, or putamen.
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