Molecular weight (DA)
55kD
Immunogen
The antiserum was produced against synthesized peptide derived from human EMR4P. AA range:101-150
Specificity
EMR4 Polyclonal Antibody detects endogenous levels of EMR4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008],
Protein name
Putative EGF-like module-containing mucin-like hormone receptor-like 4
Other name
EMR4P; EMR4; GPR127; PGR16; Putative EGF-like module-containing mucin-like hormone receptor-like 4; EGF-like module receptor 4; G-protein coupled receptor 127; G-protein coupled receptor PGR16
Human protein sequence Database
Q86SQ3
Mouse protein sequence database
Q91ZE5
Rat protein sequence database
Cellular localization
[Isoform 1]: Cell membrane ; Multi-pass membrane protein .; [Isoform 2]: Secreted .
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