Molecular weight (DA)
38kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SUCNR1. AA range:100-149
Specificity
GPR91 Polyclonal Antibody detects endogenous levels of GPR91 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009],
Function
function:Receptor for succinate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed specifically in kidney.,
Protein name
Succinate receptor 1
Other name
SUCNR1; GPR91; Succinate receptor 1; G-protein coupled receptor 91; P2Y purinoceptor 1-like
Fields
>>cAMP signaling pathway
Human protein sequence Database
Q9BXA5
Mouse protein sequence database
Q99MT6
Rat protein sequence database
Q6IYF9
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Expressed specifically in kidney.
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