Molecular weight (DA)
34kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR35. AA range:51-100
Specificity
GPR35 Polyclonal Antibody detects endogenous levels of GPR35 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in all adult and fetal tissues examined, including pancreatic islets and skeletal muscle, with relatively higher levels in adult lung, small intestine, colon and stomach.,
Function
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in all adult and fetal tissues examined, including pancreatic islets and skeletal muscle, with relatively higher levels in adult lung, small intestine, colon and stomach.,
Protein name
G-protein coupled receptor 35
Other name
GPR35; G-protein coupled receptor 35; Kynurenic acid receptor; KYNA receptor
Fields
>>Neuroactive ligand-receptor interaction
Human protein sequence Database
Q9HC97
Mouse protein sequence database
Q9ES90
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein . Internalized to the cytoplasm after exposure to kynurenic acid.
Tissue expression
Predominantly expressed in immune and gastrointestinal tissues.
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