Molecular weight (DA)
41kD
Immunogen
Synthesized peptide derived from SR-1D . at AA range: 120-200
Specificity
SR-1D Polyclonal Antibody detects endogenous levels of SR-1D protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Function
function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Protein name
5-hydroxytryptamine receptor 1D
Other name
HTR1D; HTR1DA; HTRL; 5-hydroxytryptamine receptor 1D; 5-HT-1D; 5-HT1D; 5-HT-1D-alpha; Serotonin receptor 1D
Fields
>>cAMP signaling pathway;>>Neuroactive ligand-receptor interaction;>>Serotonergic synapse;>>Taste transduction
Human protein sequence Database
P28221
Mouse protein sequence database
Q61224
Rat protein sequence database
P28565
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Detected in brain neocortex and caudate nucleus (at protein level).
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