Molecular weight (DA)
26kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NSG1. AA range:112-161
Specificity
NEEP21 Polyclonal Antibody detects endogenous levels of NEEP21 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Belongs to the NSG family.,
Function
similarity:Belongs to the NSG family.,
Protein name
Neuron-specific protein family member 1
Other name
NSG1; D4S234; Neuron-specific protein family member 1; Brain neuron cytoplasmic protein 1
Human protein sequence Database
P42857
Mouse protein sequence database
Q62092
Rat protein sequence database
P02683
Cellular localization
Membrane ; Single-pass type II membrane protein . Golgi apparatus, trans-Golgi network membrane . Endosome membrane . Cell projection, dendrite . Early endosome membrane . Late endosome membrane . Lysosome lumen . Recycling endosome membrane . Cytoplasmic vesicle membrane . Golgi apparatus, Golgi stack membrane . Endosome, multivesicular body membrane . Endoplasmic reticulum membrane . Endocytosed from the cell surface, thus enters into early endosomes, trafficks to late endosomes and degradates in lysosomes (By similarity). Endoplasmic reticulum targeting is essential for apoptosis (PubMed:20599942). Found in both stationary and motile endosomes. A previous study supports a type I membrane protein topology (By similarity). .
Tissue expression
Amygdala,Brain,Cerebellum,Testis,
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