Immunogen
The antiserum was produced against synthesized peptide derived from human RPLP2. AA range:21-70
Specificity
Ribosomal Protein LP2 Polyclonal Antibody detects endogenous levels of Ribosomal Protein LP2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes
Function
function:Plays an important role in the elongation step of protein synthesis.,similarity:Belongs to the ribosomal protein L12P family.,subunit:P1 and P2 exist as dimers at the large ribosomal subunit.,
Protein name
60S acidic ribosomal protein P2
Other name
RPLP2; D11S2243E; RPP2; 60S acidic ribosomal protein P2; Renal carcinoma antigen NY-REN-44
Fields
>>Ribosome;>>Coronavirus disease - COVID-19
Human protein sequence Database
P05387
Mouse protein sequence database
P99027
Rat protein sequence database
P02401
Cellular localization
cytosol,ribosome,focal adhesion,membrane,cytosolic large ribosomal subunit,preribosome, large subunit precursor,extracellular exosome,
Tissue expression
Epithelium,Kidney,Liver,Mammary carcinoma,Ovary,Pituitary,P
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