Molecular weight (DA)
17kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PLGRKT. AA range:1-50
Specificity
Plasminogen receptor Polyclonal Antibody detects endogenous levels of Plasminogen receptor
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.
Protein name
Plasminogen receptor
Abbreviation
Plasminogen receptor
Other name
Plasminogen receptor (KT) (Plg-R(KT))
Human protein sequence Database
Q9HBL7
Mouse protein sequence database
Q9D3P8
Rat protein sequence database
D4ACN8
Cellular localization
Cell membrane ; Multi-pass membrane protein . Colocalizes on the cell surface with urokinase plasminogen activator surface receptor/PLAUR. .
Tissue expression
Expressed in peripheral blood cells and monocytes. Expressed in adrenal medulla.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车