Molecular weight (DA)
12kD
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Specificity
MOTI Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a small peptide hormone that is secreted by cells of the small intestine to regulate gastrointestinal contractions and motility. Proteolytic processing of the secreted protein produces the mature peptide and a byproduct referred to as motilin-associated peptide (MAP). Three transcript variants encoding different preproprotein isoforms but the same mature peptide have been found for this gene. [provided by RefSeq, May 2010],
Function
function:Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.,online information:Motilin entry,similarity:Belongs to the motilin family.,
Protein name
Promotilin [Cleaved into: Motilin; Motilin-associated peptide (MAP)]
Fields
>>Neuroactive ligand-receptor interaction
Human protein sequence Database
P12872
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted.
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